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Elleste Duet

 
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Elleste Duet tablets are a combination form of hormone replacement therapy (HRT). They are used in the treatment of menopause symptoms. It has 2 active ingredients, which act as an emulation of the two female sex hormones: a synthetic version of progestogen (norethisterone) and a natural version of oestrogen (estradiol).

Product supplied may be from a different manufacturer

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Description

As a cyclical treatment, the first 16 tablets in a cycle in the Elleste Duet pack contain estradiol only. The final 12 tablets consist of a combination of norethisterone and estradiol. This reduces the risk of cancer and causes a regular period. There are three types of Elleste Duet. The 16 white tablets consist of 1mg estradiol in the 1mg pack; the 12 green tablets contain 1mg estradiol and 1mg norethisterone. The 16 orange tablets comprise 2mg estradiol in the 2mg pack; the 12 grey tablets comprise 1mg norethisterone and 2mg estradiol. Elleste Duet Conti tablets contain 2mg estradiol and 1mg norethisterone in all the white tablets.

Warnings

It's not suitable to take Elleste Duet if you:

  • Have had breast cancer before
  • May have cancer that is sensitive to oestrogen (inclusive of uterine cancer)
  • Have endometrial hyperplasia that's not yet treated
  • Have had a blood clot before or are suffering from a blood clotting disorder
  • Have recently had a stroke or heart attack
  • Have unexplained vaginal bleeding
  • Suffering from porphyria
  • Have a history of liver disease
  • Are pregnant or breastfeeding
  • Are allergic to any of the ingredients in Elleste Duet Conti
If you've had any of the following conditions before, tell your medical officer before you take Elleste Duet:
  • Fibroids
  • Impaired liver function
  • Uterine problems including endometrial hyperplasia or endometriosis
  • Circulation problems
  • High risk of blood clots
  • Diabetes
  • High blood pressure
  • Migraine
  • Gallstones
  • An autoimmune disorder
  • Asthma
  • Epilepsy
  • A history of severe allergic reactions
  • Fluid retention
  • High-fat levels in the blood
  • Obesity
  • Otosclerosis (a hereditary ear disorder)
  • A family history of breast cancer or any other oestrogen-sensitive cancer.

Directions

Elleste Duet should be taken for 28 days. If possible, you should start the medication on the first day of your monthly period. You can find information on which tablet to take next on the pill strip. Upon finishing a pack, start a new one the next day. Take the medicine at the same time each day, as indicated in the directions on the pack. Swallow the whole tablet with water. You can do this with or without food.

Ingredients

The active ingredients found in Elleste Duet include:

  • Estradiol (as hemihydrate),
  • norethisterone acetate (combined tablets only)
Elleste Duet tablets comprise the following inactive ingredients as well to make up the whole product:
  • Lactose monohydrate
  • maize starch
  • povidone
  • talc
  • magnesium
  • stearate
  • macrogol 400 and hypromellose (E464)

Side Effects

Not everybody experiences side effects after taking Elleste Duet, nevertheless, if they do, they can include:

  • anxiety
  • nausea
  • headache
  • stomach cramps
  • breast tenderness
  • change in libido
  • dizziness
  • insomnia
  • breakthrough bleeding
  • diarrhoea
  • indigestion
  • acne
  • weight gain
  • skin irritation
  • rash
  • back pain
  • discharge from the vagina
  • fluid retention
  • womb spasms
  • infection
Seek medical attention if the side effects become persistent or serious.